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A World-Class Research Environment at the Nexus of Biology, Engineering, and Physical Sciences

The Biotechnology and Bioengineering group led by Prof. Dr. Martin Fussenegger at the Department of Biosystems Science and Engineering (D-BSSE) of ETH Zurich in Basel invites exceptional candidates to apply for a PhD position in pioneering projects at the intersection of synthetic biology, nanotechnology, and bioelectronics.

The D-BSSE is ETH Zurich's first truly interdisciplinary research department uniting theoretical and experimental biology with advanced bioengineering and fostering close collaborations with leaders in materials science, physics, and chemistry to drive transformative advances in systems biology, biotechnology, and synthetic biology. Situated in Basel, Switzerland, at the heart of the BioValley, a tri-national region that hosts 40% of the global life sciences industry and numerous major pharmaceutical companies, the D-BSSE offers a unique environment for high-impact translational research with unparalleled access to academic and industrial expertise.Project background

Advancing the Frontiers of Bioelectronics and Synthetic Biology

Our group integrates state-of-the-art synthetic biology with advanced nanotechnology, and electrogenetic interfaces to engineer human cells for next generation bioelectronic medicine, designing programmable cells that respond to electrical, electromagnetic, acoustic and biochemical cues to achieve wireless, real-time control of therapeutic protein expression and metabolic regulation. Leveraging innovative platforms such as direct-current-actuated regulation, electromagnetic programming of wireless expression, and closed-loop systems, we aim to translate these technologies into clinically relevant, minimally invasive therapies for cancer, as well as metabolic, neurodegenerative, autoimmune, and infectious diseases.Job description

PhD projects will combine catalyst engineering, computational simulation, bioelectrode device fabrication, and electrical engineering to develop bioelectronic interfaces enabling closed-loop programming of cellular behaviour and real-time monitoring of metabolic activity

There will also be opportunities to design novel bioelectronic implants and develop specialized control software
Profile

We are seeking highly motivated applicants with a background in physics, material science, or chemistry

Ideally with expertise in bioelectronics or software simulations, or a strong willingness to acquire it, alongside solid knowledge of electrochemistry and materials chemistry

Candidates should be eager to collaborate closely with molecular biologists and bioengineers and demonstrate a strong academic record with the ambition to pursue a career in industrial R&D, or entrepreneurship
We offer

Your job with impact: Become part of ETH Zurich, which not only supports your professional development, but also actively contributes to positive change in society

We are actively committed to a sustainable and climate-neutral university

You can expect numerous benefits, such as public transport season tickets and car sharing, a wide range of sports offered by the ASVZ, childcare and attractive pension benefits
Working, teaching and research at ETH ZurichWe value diversity and sustainability
In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open environment that allows everyone to grow and flourish. Sustainability is a core value for us – we are consistently working towards a climate-neutral future.About ETH Zürich
ETH Zurich is one of the world’s leading universities specialising in
science and technology. We are renowned for our excellent education,
cutting-edge fundamental research and direct transfer of new knowledge
into society. Over 30,000 people from more than 120 countries find our
university to be a place that promotes independent thinking and an
environment that inspires excellence. Located in the heart of Europe,
yet forging connections all over the world, we work together to
develop solutions for the global challenges of today and tomorrow.